Chikungunya Virus in Macaques, Malaysia
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چکیده
were concentrated in Fortaleza and the northwest region of the state. Patient age distribution was significantly different between the capital, where the infection most affected children <12 months of age, and the inner cities, where it most affected persons 15–29 years of age. Current heterogeneous measles vaccine coverage (4,5); a delayed response and insufficient vaccination coverage in the past, particularly in socially disadvantaged populations from the inner cities; and difficulties in the prompt recognition and surveillance of suspected cases may explain why this outbreak occurred in a population with a vaccine coverage historically >95%. In addition, vaccination campaigns directed at children <5 years of age may not have been sufficient to interrupt the outbreak because a substantial number of older persons were susceptible. Most notably, because it has lasted >12 months, Ceará’s current outbreak may represent the reestablishment of endemic transmission of measles in the Americas.
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been reported to be seropositive for CHIKV (2,6–8). These results indicate that CHIKV infects long-tailed macaques in Malaysia, but seroprevalence rates are low, and there is little evidence of viremia, except at the 1 specific site in Kuala Lipis. Although experimental infection of long-tailed macaques resulted in detectable CHIKV an-tigen in macrophages for >3 months, infectious CHIKV is not ...
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